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KMID : 1138520080110010041
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Journal of Pharmacopuncture
2008 Volume.11 No. 1 p.41 ~ p.54
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Effects of Sweet Bee Venom and Bee Venom on the Heart Rate Variability
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Yook Tae-Han
You Jeong-Seok
Jung Han-Sung
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Abstract
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Objective : In this study, we investigated the effects of Sweet Bee Venom(SBV) and Bee Venom(BV) at a acupoint, HT7(Shinmun) on the Heart Rate Variability(HRV) in the healthy man. And we tried to observe how Sweet Bee Venom and Bee Venom affects on the balance of the autonomic nervous system.
Methods : We investigated on 22 heathy volunteers consisted of 10 subjects in SBV group and 12 subjects in BV group. Study form was a randomized, placebo-controlled, double-blind clinical trial. 22 subjects of each group were injected SBV and BV at HT7(Shinmun). And we measured HRV by QECG-3:LXC3203 (LAXTHA Inc. Korea) on 7 times : before and after injection per 5minutes during 30minutes.
Results : 1. After SBV injection, Mean-RR was significantly high from 0 to 10 minutes, Mean-HRV was significantly low from to 10 minutes, SDNN was significantly high after 25minutes, Complexity was significantly high from 5 to 10 minutes and RMSSD was significantly high from 5 to 10minutes. 2. Complexity of SBV Group significantly decreased from 20 to 25minutes, RMSSD of SBV Group significantly increased from 10 to 15minute and from minutes, SDSD of SBV Group significantly increased from 10 to 15 minute and from minutes compared with that of BV group. 3. After SBV injection, Ln(VLF) was significantly from 25 to 30minutes.
Conclusions : The results suggest that SBV in heathy adult man tend to activate the autonomic nervous system compared to BV within normal range.
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KEYWORD
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Sweet Bee Venom, Bee Venom, Heart Rate Variability, Sweet BV, BV, HRV
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